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Intra Uterine Insemination:

Intrauterine insemination with partner's sperm can be used as a potentially effective treatment for infertility of all causes in women under about age 45 except for cases with tubal blockage, severe tubal damage, very poor egg quantity and quality, ovarian failure (menopause), and severe male factor infertility.

Intra Uterine Insemination

Intrauterine insemination (IUI) is a procedure that allows the physician to deposit specially washed and prepared sperm directly into the uterus via a small flexible catheter. IUI allows the sperm to bypass the cervix; therefore more are available to fertilize the egg(s). Unwashed sperm should never be placed into the uterus as serious, even fatal, allergic reactions can occur.

It is most commonly used for infertility associated with endometriosis, unexplained infertility, anovulatory infertility, very mild degrees of male factor infertility, cervical infertility and for some couples with immunological abnormalities. It is a reasonable initial treatment that should be utilized for a maximum of about 3-6 months in women who are ovulating (releasing eggs) on their own. It can be reasonable to use it for somewhat longer than this in women with an ovulation that has been stimulated to ovulate.

IUI is responsible for most high order multiple births discussed by the mass media. This is because the exact number of eggs ovulated cannot be precisely controlled. In IVF, a known number of embryos are placed in the uterus, thus limiting high order multiple births (>=3). FSH stimulated cycles should only be managed by a physician thoroughly trained in the use of fertility medications.

IUI requires that the husband bring a semen sample to the Andrology Lab (see Andrology Lab Information or Handout) for semen sample washing. The sample can be collected at home, or on site in a collection room.

Our office will call the Andrology Lab to schedule a sperm preparation appointment, usually between 8:30 and 9:00 a.m. The sample is then processed (it takes approximately 1 hour) and concentrated by our laboratory. Plan to return to the office at the scheduled time, usually between 10:30 and 11:30 a.m. for the insemination. The insemination procedure usually takes a few minutes. During the procedure, some patients experience minimal cramping. Afterwards, normal activities can be resumed.

Sperm Preparation for IUI

If you are being treated with IUI using husband's sperm, a nurse or physician will notify you of the appropriate time to perform the insemination. IUI procedures are usually performed the day after an LH-surge is detected, or 36 hours after HCG is administered. Typically, semen is processed starting at 8:30-11:30 a.m., with the IUI performed 2 hours later. Instructions for collected semen are similar to those for a semen analysis above.

Our office will schedule the sperm washing procedure with the Andrology Lab. When scheduled, please bring the semen specimen to the appropriate Andrology Lab. Please pick up the washed specimen prior to your scheduled IUI time, and deliver it to our office. When you arrive, please inform us that you have a semen specimen so that we may place it in our incubator prior to your IUI.

 

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